This movie is about a couple of charming runaways on the lam. They haven’t committed any crimes but they’re keen to evade the responsibilities that weigh on them at home. We’ve seen lots of movies about people on the open road, but we’ve rarely seen a man beleaguered by Alzheimer’s helming a large winnebago while his cancer-stricken wife navigates and their adult children are panicking at home.

Ella (Helen Mirren) should be in the hospital receiving treatment, but instead she’s choosing this one last hurrah before Alzheimer’s has her husband John (Donald Sutherland) completely within its clutches. The Leisure Seeker is the name of their beloved RV, and this road trip is designed to trigger memories of happier times – their young family at play, their former selves in love. It’s obvious that the ‘in love’ part has never really faded for Ella and John, and maybe this is why it’s so hard for her to cope when he can’t remember who she is.

The pair hit the interstate armed with pecan logs, slides of old photos, and yes, a gun. This film is a moving eulogy to all the things that are slipping away – not just for John and Ella personally, but also perhaps on a more national scale (like a sense of community for one – though attempts to be any more political feel out of place). But as John’s moments of lucidity grow shorter and Ella’s anguish grows deeper. The Leisure Seeker is pointed toward Florida but we can’t deny what they’re truly headed for.

Mirren and Sutherland make the movie of course – the camera rarely strays from this couple so strongly bonded they can’t even bear to sleep in separate beds. Sutherland spins the dial on the many shades of dementia, his face quietly registering all of them. Mirren wears a cheerful mask but Ella’s pain and smouldering anger never disappear completely. This Brit and her Canadian costar make watching this American road trip movie worth while – even if their Italian director doesn’t quite get it right. The acting, however, is everything, and the casting is spot-on even if Mirren is inconsistent with her southern accent. Just as we’re meeting them, they’re getting ready to say their goodbyes. This is a bittersweet journey, and you’re welcome to tag along. You can leave your gun at home, but do pack some tissues.